There are inherent complexities of evenly assessing 'quality' in a methodologically heterogeneous group of studies such as these, 12 and debate in the literature about how to integrate the findings (if at all) of studies assessed as lower quality.
Dr. Stampfer and others say its analysis is methodologically flawed, because it includes data from widely heterogeneous studies, excludes data from hundreds of others for unclear reasons and does not try to detail the causes of increased mortality among supplement users.
Because the studies were so therapeutically and methodologically heterogeneous, results are reported separately for each article.
Moreover, such studies about ascending aorta aneurysms are methodologically heterogeneous, with respect to the biomechanical parameters and the mathematical models utilized in the analysis of aortic wall elasticity: therefore, experimental results are still inconclusive and often conflicting so far [ 3– 6].
Here, we try to offer an original aggregation pattern of the data, which are mostly very recent but often incomplete and methodologically heterogeneous, to highlight research trends and gaps of knowledge, also in relation to experimental rodent studies.
Methodologically, the studies were strong but did not adequately address affordability and sustainability and were also highly heterogeneous in terms of settings and LHW outcomes, limiting their comparability.
Forest Ecosystems will encourage methodologically diverse studies, employing both quantitative and qualitative approaches.
Reporting bias was minimised by including all available methodologically sound studies (published or not).
Unfortunately, few methodologically rigorous studies exist to guide clinical practice.
