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OPN has been shown to amplify Ccl-2 mediated migration of macrophages [19].
We have previously demonstrated that both C2C12 and primary myoblasts express both of these receptor subtypes and therefore either could regulate Ang II mediated migration.
Most importantly, we observed that estradiol mediated migration and invasion of thyroid cells is dramatically abrogated by DIM when DIM and estrogen were added together in cell cultures.
WASP has been previously implicated in ROBO4 mediated migration of HEK-293T cells [ 27].
Parallel studies of RA and OA fibroblasts have also found that CCL19/CCL21 mediated migration [ 37].
Therefore, the first model does not explain the ecto-ErbB4 mediated migration.
Similar(53)
We further find that the MAPK pathway is an important mediator of LPA chemotaxis and invasion, but is dispensable for EGF-mediated migration.
Changes in the cytoskeleton were observed including cytoskeletal-mediated migration, adhesion, and invasion.
This shows that PIP3 polarization and PI3K-mediated migration both require actin polymerization.
These data suggest that CXCL12-mediated migration of ESNPs requires the function of CXCR4.
This process is dependent on CXCR4-mediated migration of hematopoietic stem cells (HSCs) [2], [4], [29].
Related(20)
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regulated migration
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