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While both the DEL and EVL showed highly coordinated migration toward posterior sites in control embryos (Fig. 7, left column; Supplementary Movie S1), cells of the DEL in cfl1-morphants did not form tight attachments and showed a clear gap with EVL cells (Fig. 7, right column; Supplementary Movie S2).
This study further highlights the importance of sequential receptor tyrosine kinase activation to achieve coordinated migration of all glial cells, as abnormal glial migration is a feature of many human diseases.
Coordinated migration of endothelial cells models the remodeling of existing endothelia as well as angiogenesis and vasculogenesis.
Numerical simulations show that the role of aversion to poverty is negligible when considering each country separately, but becomes important for the design of a coordinated migration policy.
Doyle et al. observed a coordinated migration in fibroblasts moving on thin (1D) lines with a width of up to 5 µm [1].
and found that coordinated migration was rare.
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Brinker also is founder of "Project Owlnet", a non-profit organization devoted to conservation of Saw-whet Owls that encourages, facilitates, and coordinates migration monitoring as well as facilitates communication between a network of Saw-whet Owl banding stations across North America.
Frontex was conceived over a decade ago to coordinate migration issues across Europe.
The androgen-driven assembly of AR/FlnA/integrin beta 1 complex induces activation of Rac 1 and FAK, which both coordinate migration.
These physical factors are ubiquitous in the physiological setting and can act in synergy to coordinate migration of fibroblastic cells.
We prove that Axl is able to coordinate migration per se and by ChIP and promoter analysis we observe that its transcription is directly driven by AP-2α via the binding to one or more functional AP-2α binding sites present in its regulatory region.
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