Sentence examples for mediate different cellular from inspiring English sources

This catalytic activity is dependent on its interaction with an E2 variant (Uev) and Ubc13 associated with different Uevs is thought to mediate different cellular processes (Andersen et al. [2005]).

MicroRNAs (miRNAs) are small noncoding RNAs (sncRNAs) known to mediate different cellular functions through post‐transcriptional regulation (Djuranovic et al., 2011).

Both the precursor (Progranulin) and the degraded forms (Granulins) mediate different cellular effects in a variety of pathophysiological conditions such as inflammation, proliferation, carcinogenesis and wound healing [ 25].

Both PI3K and MAPK pathways crosstalk extensively with the mTOR pathway to mediate different cellular functions through two different proteins, ribosomal protein S6 kinase (S6K) and 4E-binding protein (4EBP) [ 8].

It has been proposed [ 2] that different TRGC genes, each possessing unique connecting regions [ 22], could mediate different cellular responses after the T cell receptor has engaged the antigen.

Since p75NTR is a cell-surface receptor that binds a variety of ligands to mediate different cellular effects, it was important to determine whether the inflammatory cytokines not only increased expression of this receptor in the neurons and astrocytes, but whether the elevated receptor was on the cell surface where it may be activated by ligand.

Moreover, RalBP1 was shown to be proteolyzed into several fragments with differential subcellular localization, suggesting the proteolyzed fragments mediated different cellular functions.

Thus, the finding that differential binding of p53 phosphorylated at S46 to a specific subset of target genes might influence the p53 target gene choice is most likely one of several regulation layers that are required to mediate the different cellular stress response.

In turn, GTP-bound active GTPases can interact with a plethora of different effectors which mediate the different cellular functions of this family of proteins.

p75NTR is induced in CNS neurons after many types of injury (Kokaia et al., 1998; Roux et al., 1999; Casha et al., 2001; Ramos et al., 2007), and can mediate many different cellular responses, including neuronal apoptosis or survival, and regulation of axonal growth (Rabizadeh et al., 1993; Frade et al., 1996; Maggirwar et al., 1998; Friedman, 2000).

These data indicates that growth on 3-HPA and 4-HPA are mediated by different cellular enzymatic components.