Sentence examples for mediate different biological from inspiring English sources
Rho-kinases (ROCKs), are one of the dynamic structures of the actin cytoskeleton and they mediate different biological processes, including regulation of calcium sensitivity of smooth muscle contraction.
Since these two ER subtypes are thought to mediate different biological effects, there is intense interest in designing subtype-selective ER ligands.
Thus, in addition to its requirement for cell viability, Ras appears to mediate different biological roles depending on the developmental context and on the level of its expression.
Similar to phosphorylation, acetylation has been shown to both promote and decrease FOXO transcriptional activity and to mediate different biological functions of FOXOs [ 36, 37].
Collectively, our data may suggest that HIF-1α/GPER signaling mediates different biological outcomes in CAFs exposed to hypoxia.
It has been reported that intracellular Gal-1 mediates different biological functions through its interaction with H-Ras.
This analysis revealed six important upstream regulators, each predicted to act upon different sets of target molecules, likely mediating different biological effects.
Up to now, there have been no comprehensive 3D structural analyses of WD40 protein revealing the interacting partners and highlighting the relevance of WD40 domains mediating different biological functions [ 9].
Food odors and pheromone signals have been shown to project to non-overlapping divisions in higher brain regions in Drosophila, suggesting that distinct brain divisions may be involved in mediating different biological functions (Jefferis et al., 2007).
In particular, a profusion of cytoplasmic signalling effectors, binding phosphorylated tyrosines via Src homology domain type 2 (SH2) and type 3 (SH3) and phosphotyrosine binding domain (PTB), can be recruited upon receptor activation by their ligands, to mediate multiple, qualitatively different, biological responses to a given factor.
This finding could suggest that each PC could display different biological effects mediated by this kind of cell when used clinically.
