Sentence examples for mediate a protective from inspiring English sources

Several HIF-1 target genes have been shown to mediate a protective effect on the mucosal layer through the upregulation of CD55, ecto-50 nucleotidase, MUC-3, intestinal trefoil factor, and P-glycoprotein [21].

By contrast, low doses of MG132 mediate a protective response against oxidative stress [ 20].

We hypothesised that a gut microbiota-derived metabolite, that is increased upon ITF treatment and specifically targets liver tissue, could mediate a protective effect.

Additionally, hyperthermia results in an increased cellular level of heat shock proteins (HSPs), which are believed to mediate a protective effect against skeletal muscle damage [ 57].

However, the duration of the T15-id IgM intervention or the levels achieved by the infusion strategy may not have been sufficient to mediate a protective effect in these studies.

In contrast, the A2B receptor has been shown to mediate a protective effect against endotoxin-induced sepsis, by regulating inflammation and vascular adhesion (Yang et al., 2006) and against cardiac fibrosis, by modulating cardiac fibroblastic proliferation (Chen et al., 2004).

The results suggest that ACh mediates a protective effect on myofibers that is independent of postsynaptic activity.

However, recent studies have suggested that immunization with UpaG mediates a protective effect against challenge with virulent extraintestinal isolates of E. coli in mouse models of infection [73].

In particular, a mutation in the pyruvate kinase gene has been identified as mediating a protective mechanism to P.chabaudi infection involving increased splenic clearance of erythrocytes through hemolysis [10], [11].

This leads to the assumption that TN-R, by way of forming stable aggregates, has a relevant part in mediating a protective aspect of the PNs.

During Ebola infection, the antibody titer represents the best correlate of protection, however several evidences suggest a key role of T cells in mediating a protective immune response.