Sentence examples for mediate a positive from inspiring English sources

The IRF3/IRF7, NF-κB, and AP-1 bind to PRD I/III, PRD II, and PRD IV, respectively, where they promote the transcription of IFN-α, IFN-β, and pro-inflammatory cytokines (TNF, IL6, IL1β, etc).. Following production, IFN-α and IFN-β mediate a positive feedback-production loop by binding to the IFN-α/β receptor (IFNAR) in an auto- and/or paracrine manner.

The factors that mediate a positive correlation between ASP and MTV include spatial resolution and necrosis.

Elevated concentration of endothelin-1 mediateiate a positive response to inhaled nitric oxide.

This active suppression by CTLA-4 expressing CTLA-4 expressinghe possibiliTr that cells4 engagement may mediate a positive signal foraiseslathey function.

Thus, Stat6 is likely to mediate a positive feedback loop in the progesterone response that is crucial for the delayed and sustained action of progesterone on breast cancer cells.

28 In addition to these previous observations, our study suggests that IL-1α and IL-8 mediate a positive feedback loop between PIM2 and STAT3, thereby allowing constitutive activation of STAT3 in breast cancer cells.

Kwon, J. et al. The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling.

Bem1 may induce cell polarization by mediating a positive feedback loop whereby Cdc24 is preferentially recruited/activated at the site of Cdc42GTP accumulation [19], [20], [21].

Similarly, upregulation of ppk1 encoding polyphosphate kinase increases polyphosphate levels and enhances activation of the MprAB two-component system [47], mediating a positive feedback loop through SigE [3].

These data indicate that Stat6, as both a PR cofactor and a target gene, mediates a positive feedback loop participating in the growth-inhibitory response to progesterone.

It could be that the relationship with "the home" was reflected in the staff's body language who mediated a positive interest and engagement.