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Extended-release formulations may reduce toxicity with a lower maximum blood concentration (Cmax) and improve efficacy with a higher minimum blood concentration (Cmin).
Supplementation with organic or inorganic forms of selenium (Se) may reduce toxicity following exposure to a wide variety of environmental chemicals.
Targeted drugs that can cooperate with doxorubicin to kill TNBC may reduce toxicity and improve outcome.
Previous studies have also indicated that phosphorylation of Tau may reduce toxicity (Thies and Mandelkow, 2007).
In addition, drug combinations may reduce toxicity and side effects that single targeted drugs may cause.
The potential advantage of this conjugate is that trastuzumab targets DM1 specifically into tumor tissues, which may reduce toxicity.
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Selective delivery of antiretrovirals to human immunodeficiency virus (HIV) infected cells may reduce toxicities associated with long-term highly active antiretroviral therapy (HAART), may improve therapeutic compliance and delay the emergence of resistance.
A sequential-type approach may not only reduce toxicity but might also help to overcome any antagonism which may exist between agents – one possible reason for the failure of paclitaxel carboplatin to improve survival over carboplatin alone in the ICON3 trial (International Collaborative Ovarian Neoplasm Group, 2002).
Radiotherapy that selectively avoids irradiating highly-functional lung regions may reduce pulmonary toxicity.
Focal therapy may reduce the toxicity of current radical treatments while maintaining the oncological benefit.
While bacterial colonization of soil may reduce the toxicity of chlorothalonil to native soil biota, enzymes, and plant roots.
Related(20)
may reduce exposure
may decrease toxicity
may reduce concentration
may reduce harm
may reduce dose
may reduce toxin
may reduce acute
may reduce effects
may reduce turbulence
may reduce signal
may affect toxicity
may overpredict toxicity
may reduce return
may reduce demand
may reduce inflammation
may mediate toxicity
may underestimate toxicity
may reduce service
may reduce crop
may reduce unhappiness
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