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We hypothesized that TPVB combined with general anesthesia may reduce acute and chronic postoperative pain after BCS.
There's little to no evidence to show that opioids are effective in treating pain, except in cancer". Opioids may reduce acute pain, but they do not address the root causes of chronic pain.
The authors hypothesize that rhAPC may reduce acute organ dysfunction, thereby diminishing the likelihood of chronic dysfunction and thus improving long-term HRQoL.
Our results and other published studies showed that timely diagnosis and intervention, including the use of IVIG infusion, may reduce acute mortality [ 10, 17- 19].
In two randomized trials [ 25, 26] comparing IMRT to two-dimensional breast planning, improved homogeneity translated into reductions in acute toxicity supporting the need that an accurate evaluation of dose homogeneity, before treatment delivery, may reduce acute severe skin reactions.
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Early treatment of allografts with agents like dnCXCL8 may help reduce acute allograft damage and preserve renal morphology and thereby help limit chronic dysfunction.
Thus, suppression of NO production may help reduce acute inflammation.
The use of a weekly oxaliplatin schedule may, in addition, reduce acute toxicity and maximise the inhibition of sub-lethal radiation-induced DNA damage repair (Aschele et al, 2005).
Introducing amide bonds into a steroid nucleus or its side chain may reduce the acute toxicity and enhance the pharmaceutical activity.
This may reduce the acute toxic effects associated with certain metals, e.g. Ag, Cd, Cr, Cu, Ni and Pb, but some researchers have also reported increased bioaccumulation of others, e.g. Hg in aquatic organisms [15].
Therefore, early intervention to prevent or reduce acute toxicity may be worthwhile in the long term.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com