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Slightly different preferences for RNA-binding, but also in the expression levels of PUM proteins may influence binding with alternative outcomes for the fate of the mRNA.

This amino acid is located in the antigenic site Ca2 in the immediate vicinity of the receptor binding pocket and it may influence binding preferences of the virus [9], [10].

To determine if other motifs are present in the C-terminal tail of NOXO1 that may influence binding of the tandem SH3 domains to p22phox, ITC titrations were carried out with constructs harbouring the tandem SH3 domains plus the C-terminal portion of NOXO1 (referred to as SH3AB E).

Other factors, such as chromatin structure, may influence binding of Zap1 to the ZRG17 promoter.

Thus, the lack of a correct orientation of the CBM relative to the CelE catalytic domain may influence binding and/or reactivity.

It is therefore likely that tissue-specific differences may influence binding of MSL complex on the X chromosome and that may also in turn be influenced by the expression status of the X-linked genes (Sass et al. 2003).

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These subtle differences in glycosylation may impact the patient experience as changes in glycosylation may ultimately influence binding, immunogenicity, and effector activity[ 8].

Likewise, nine CREE 5' of CDSs contain IHF-binding sites that may influence the binding and action of other proteins, including RNA polymerase and RNase III.

The model assumes that adsorption is a cooperative phenomenon, with the ligand binding ability at one site on the macromolecule, may influence different binding sites on the same macromolecule [109, 110].

However, these artificial lipid-mimicking molecules may influence the binding of hydrophobic ligands, as observed in the case of a steroid binding site in cytochrome c oxidase where a systematic analysis of detergent effects led to a clearer understanding of competitive behavior between ligands and detergents and a more precise definition of the binding domain.

In addition, tau concentration may influence paclitaxel binding affinity to microtubules [ 12] and paclitaxel and tau may compete for the same β-tubulin binding sites [ 13].

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