Sentence examples for may induce pathological from inspiring English sources

However, studies show that IL-17 overproduction may induce pathological effects during Mtb-induced inflammation [ 17], although its role in establishing clinically cured TB in humans still needs to be determined.

An imbalance of Ca2+ flux may induce pathological conditions such as arrhythmia and decreased contractility of the cardiomyocytes.

In conclusion, the effects of α-synuclein remain controversial: several reports indicate that even the wild-type form of the human protein may induce pathological changes.

Therefore, we hypothesize that NGF is upregulated following annular rupture and may induce pathological changes, such as nerve ingrowth and sensitization, in the disc.

On the other hand, as Rho GTPases are 'molecular switches' for transferring signals from chondrocyte extracellular matrix to downstream effectors, 20 Rac1 may induce pathological changes to chondrocytes via its downstream effectors.

Thus, redox modulation of cellular proteins comes in "different flavors"; while moderate reversible oxidations may increase protein activity, and a more sustained ROS may induce pathological modifications through stable interactions with lipids, proteins, and DNA (40).

Thus, hypothetically, cytokines may also induce pathological changes in the nerve fibers in the long term.

Similar events are hypothesized to occur in other protein misfolding diseases such as Alzheimer's, Huntington's and Parkinson's in which protein agents may similarly induce pathological protein states.

However, the persistence of p-eIF2α coupled with eIF4G degradation may induce a pathological transition that results in a disproportion at expression of proapoptotic genes due to residual translation (Wek et al., 2006).

Results of this study show that perturbations in microenvironmental factors result in anatomical and gene expression change within the intervertebral disc that may ultimately compromise cell function and induce pathological deficits.

The present preparation, in combination with transgenic animals and other techniques, may allow the study of the extrinsic and intrinsic components that induce pathological activity.