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Exact(6)
Similarly, chemical lysis may affect enzyme activity detrimentally by disrupting enzyme complexes, etc.
In addition, genetic variability in the coding of various CYP genes may affect enzyme activity (reviewed by Daly et al. 1994; Ingelman-Sundberg 2001).
Four substitution mutations (Arg107His, Arg108Trp, Gly110Ser, and Arg516Gln) are observed at positions with very high structural conservation (>80%, residues are red in Figure 6B) and therefore may affect enzyme structural core.
The buried site Asn71Tyr lies in catalytic domain β-strand structure where it may affect enzyme stability due to introduction of large hydrophobic residue in place of smaller hydrophilic one.
Several genetic variants have been described in regions next to these regulatory sites that may affect enzyme expression [ 9, 10] and contribute to a greater risk of developing cancer.
The same study demonstrated that serum DPPIV from SLE patients was also hypersialylated but activity was not restored following neuraminidase treatment, from which it may be inferred that differential post-translational glycosylation may affect enzyme activity and/or substrate preference.
Similar(54)
Further, conformational changes in tannase structure in response to amino acid ionization may also affect enzyme activity (Sabu et al. 2006).
Working with a system with low water content may directly affect enzyme performance.
Finally, we show that genome size, repetitiveness, methylation status, and quality of the associated reference are all factors that may ultimately affect enzyme selection.
In this study, differences between highly and less neuroinvasive lineage 2 stains were identified in the noncoding regions, which may potentially affect enzyme binding sites and replication efficiency.
This indicates that in Amoroso RZ, the cold storage may specifically affect enzymes involved in conversion of lycopene or its precursors to 6-methyl-5-hepten-2-one.
Related(20)
may influence enzyme
may affect inhibitor
may affect activity
may affect protein
may affect economic
may promote enzyme
may affect vulnerable
may exert enzyme
may improve enzyme
may trigger enzyme
may affect clinical
may alter enzyme
may disrupt enzyme
may increase enzyme
may affect early
may affect EPCs
may affect individual
may compromise enzyme
may encode enzyme
may decrease enzyme
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