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Moreover, incubation of enzymes at extreme conditions may trigger enzyme aggregation or precipitation.
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The additional oxygen atom may alter the stability of the substrate, leading to other molecular rearrangements (Coon et al. 1996; Bergé et al. 1998), or it may trigger conjugation by enzymes such as glutathione-S-transferases (reviewed in Tu and Akgül 2005).
The difference in the phosphorylation/dephosphorylation of substrates downstream of these two enzymes may trigger fast and slow gene transcription, respectively.
For example, protein phosphorylation may trigger substrate degradation by proteolytic enzymes, direct intracellular protein sorting or drive the assembly/disassembly of active complexes in signaling, transcription, translation, cell division and organelle biogenesis.
In addition, the ingestion of sucrose may trigger the production of other digestive enzymes that could have an indirect detoxifying role.
She went on: "Hoppin' John is also rich in allyl sulfides, which trigger enzymes that facilitate carcinogen excretions.
The generation of blood coagulation enzymes in the tumour microenvironment may trigger the activation of PARs (protease-activated receptors).
It is also possible that Zn2+ may trigger extra-mitochondrial effects which are not prevented by microsomal enzymes such as MGST1.
Finally, Asm is a pH-sensitive enzyme, and the activation of redox processes by pyocyanin may trigger a change in pH, in particular an acidification of the matrix that increases the activity of Asm and the generation of ceramide.
These oxido-reductase enzymes produce and utilize a large variety of secondary metabolites [ 22] which may trigger M. phaseolina to survive in a wide range of physical environments and facilitate to infect new plant species.
Lack of employment opportunities may trigger violence and juvenile delinquency.
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