The TPH2 gene is an obvious candidate to genotype because in theory low activity of this enzyme may decrease the amount of serotonin available in the brain.
Salmonella-induced damage to the small intestine may decrease the villi-associated enzyme activity, causing malabsorption of nutrients and diarrhea, and thus contribute to the symptoms of infection.
Although the liquefaction and solubilization of the substrate may decrease the probability of the enzyme to bind with the substrate, a surprisingly high yield, above 60% glucose of total, could be obtained even with the mixture of enzymes lacking the CBM after 120 hours.
Gene disruption studies have shown that the virulence of fungal phytopathogens may decrease significantly when a pectinolytic enzyme gene is mutated [ 31], although in most cases more than one gene has to be mutated to affect virulence, owing to redundancy between multiple isoforms of these genes in the fungal genomes [ 32].
It appears that corn oil may decrease expression of some gluconeogenic enzymes compared to those steers that were fed with non-supplemented feed, where as those steers fed with corn grain would have a higher expression of gluconeogenic enzymes with respect to the grazing treatments.
Thus, minor SNPs linked to the APS haplotype may compensate for the decreased enzyme thermostability produced by the met158 allele.
To date ten variant NOS3 alleles have been identified in this region, these are, or may be, associated with decreased enzyme activity [ 13].
Similarly, muscle enzyme levels may be inadequate since they are not specific, may decrease even with ongoing muscle inflammation and may be elevated in non-inflammatory myopathies and in denervating conditions [ 3].
Smoking may decrease organochlorine concentrations by enhancing their metabolism via smoking-related induction of cytochrome P450 enzymes (Deutch and Hansen 1999; Zevin and Benowitz 1999).
For some workers, hours may decrease.
