Sentence examples for matched normal mammary from inspiring English sources

Both tumor genotypes showed gene deletions and/or amplifications compared to their jnk2 matched normal mammary glands (Table 1), consistent with the presence of genomic instability we observed in Figure 2. PyV MT/jnk2−/− tumors showed additional chromosome segments that were amplified or deleted compared to the PyV MT/jnk2+/+ tumors.

cDNAs were generated from matched normal mammary gland and mammary gland tumors from DMBA-treated CD1 wild-type mice (n = 6, same as in Figure 2A).

Cyp1b1 was also increased in mammary tumors compared with matched normal mammary glands in the mammary cancer cohort (p < 0.05; Figure 4D).

In a further study, RAI3 overexpression was observed in 19 of 25 breast cancer samples compared to matched normal mammary gland tissues and in 6 of 11 breast cancer cell lines.

Semi-quantitative RT-PCR analysis showed significantly increased expression of mouse S100A7/psoriasin mRNA in mammary gland tumors relative to matched normal mammary gland (p < 0.05) by Wilcoxon signed-rank test, one-sided.

For example, a mouse transcriptomics study investigating gene expression in MMTV-neu tumors found that PADI2 expression was upregulated ~2-fold in hyperplastic, and ~4-fold in primary neu-tumors, when compared to matched normal mammary epithelium [ 12].

The fixed effects of tissue status (with tumor or normal) and maternal TCDD, their interaction, and litter as a random effect were modeled for Comt and Cyp1b1 levels in mammary tumors and matched normal tissue (Proc GLM).

To look for evidence of possible tumor cell contamination or field cancerization by genetic effects, a pilot study (Study 1: 12 sample pairs) followed by a verification study (Study 2: 20 sample pairs) were performed on DNA extracted from HER2-positive breast tumors and matching normal adjacent mammary tissue samples excised 1 3 cm beyond the invasive tumor margin.

The DNA samples from mammary carcinoma cell lines HCC-18066, HCC-11433, HCC-1428 and HCC-1937) and matched normal cell lines were received from Dr R Parson of Columbia University, New York, USA.

All the cases had matched normal tissues.

The levels of expression in these neoplasms were matched to normal mammary gland tissues from virgin, lactating, involuting, and nonpregnant multiparous females.