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In both sets of experiments, NFD fed, age matched normal weight mice served as normal controls.
Accordingly, compared to age matched normal weight controls, serum levels of anandamide are increased in patients with AN.
In a cross-sectional study, de Beer et al. compared HRQoL in obese Dutch adolescents to age and sex matched normal weight controls (n = 62) [ 32].
For example, when combined with smoking and/or psychological distress, an overweight individual had costs that were approximately CAD$2000 greater over 11.5 years than did a matched normal weight individual with no other risk-factors present at baseline.
Similarly, an obese individual with other lifestyle risk-factors present had between CAD$2,700 to CAD$7,000 higher costs over 11.5 years than did a matched normal weight individual with no other risk-factors present at baseline (Table 4).
Obesity accounts for nearly $80 billion per year and between 2% and 3% of total health care expenditures in North America [ 1] a 6%to45%5% relative increase in health care expenditures when compared with age and gender matched normal weight populations [ 2].
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After matching, normal weight (p=0.001) and overweight SLE (p=0.01) subjects still had significantly higher plasma leptin levels than matched controls (online supplementary table 1).
The results of the N+IR and O+IR patients were compared to age, gender, BMI, disease duration and smoking status matched normal-weight patients without IR (N-IR) and obese patients without IR (N-IR), respectively.
One eye tracking study by our workgroup 10 delivered evidence that people with BED differ from age-matched and weight-matched overweight/obese controls and age-matched normal weight controls concerning an increased general and food-related impulsivity.
In conclusion, our study demonstrated that the incremental long-term medical expenditures associated with obesity among a middle-aged population are modest as compared with propensity-matched normal weight controls.
For example, overweight and obese individuals who had 3 other lifestyle risk-factors (i.e.., sedentary lifestyle, cigarette smoking, psychologically distressed) had on average, $1,868 and $7,156 higher total expenditures respectively over 11.5 years of follow-up, than did propensity-matched normal weight healthy controls.
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