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It contained 48 formalin-fixed and paraffin-embedded human GIST tissue specimens and 9 matched normal gut tissue specimens.
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All the cases had matched normal tissues.
All matched normal DNA showed KRAS and BRAF wild-type.
Variant calling is commonly performed against a matched normal.
All matched normal DNA showed KRAS wild-type.
None of the matched normal tissues showed methylated bands.
All these insert bands were absent from the matched normal.
All samples were tested against matched normal DNA.
175 age and sex matched normals were also included.
Moreover, matching normal DNA is not mandatory in most cases.
Only GSE21124 data set was analyzed by matching normal samples.
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CEO of Professional Science Editing for Scientists @ prosciediting.com