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Urine markers have been studied extensively but cannot be easily standardized due to diuresis variations, and blood prognostic markers for bladder cancer are lacking.
We will discuss our plans to establish a multi-institutional bladder cancer data base and virtual tumor bank as a resource for participating institutions to evaluate the biological and prognostic significance of potential markers for bladder cancer.
We previously screened proteins as tumor markers for bladder cancer by proteomic analysis of cancerous and health tissues and identified some proteins, calreticulin et al, as markers [1] [3].
MicroRNAs have also been shown to be potential urinary markers for bladder cancer (Hanke et al, 2009).
Among the recently developed diagnostic markers for bladder cancers, those based on aberrant DNA methylation appear to be highly promising.
Conclusion: Survivin RNA and MMPS zymography can be considered as promising noninvasive markers for bladder cancer early detection.
Similar(51)
Our data suggest that ETK may potentially serve as a drug target and prognostic marker for bladder cancer.
In addition, we can say only that Bmi-1 expression is an independent prognostic marker for bladder cancer.
Indeed, measurement of ADAM12 appeared to be a more sensitive diganostic marker for bladder cancer that standard cytology.
KPNA2 is a novel independent prognostic marker for bladder recurrence, DFS and OS of UTUC patients who have undergone RNU.
Here, we present HRG4 as a novel prognostic marker for bladder cancer patients, especially when coexpressed with HER4.
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