Sentence examples for many somatic tissues from inspiring English sources

Although Nanos3 is transcribed both in germ cells and in many somatic tissues, efficient translation of NANOS3 protein occurs only in germ cells.

In contrast, the presumptive promoter identified here, which directs expression of brain mRNAs initiating upstream of coding exon five, is likely to direct expression of sAC in many somatic tissues.

In complex organisms such as mammals, many somatic tissues such as bone marrow are capable of renewal, repair, and even regeneration.

Our analysis of RNA-seq data, in consideration of several mitigating factors, indicates that gene expression from the X chromosome in mammals is up-regulated in many somatic tissues.

Our analysis shows that the high number of paralogous gene families on the mammalian X chromosome relative to autosomes contributes to the ambiguity in RXE calculations, RNA-seq analysis that takes into account that single- and multi-copy genes are compensated differently supports the conclusion that, in many somatic tissues, the mammalian X is up-regulated compared to the autosomes.

This understanding, that a shared placenta during development led to hematopoietic but not other tissue chimerism, persisted until recently, when investigators using modern genetic techniques were able to detect chimerism in many somatic tissue types and even in the germ line [ 24].

In many normal somatic tissues 3.3-kb repeats are mostly but not completely methylated, and they are hypomethylated in glioblastomas, leukemia cell lines, tissues of patients with FSHD and with DNA methyltransferase deficiency syndrome ICF [ 20- 24].

Thus, male germ-line tissues seem to accumulate fewer short telomeres than male somatic tissues.

Recently, a study extended these findings to identify chimerism in many tissues, including somatic tissues from other lineages and germ cells.

Many are expressed in both sexes at some point in development (Perry et al. 2014), and many are expressed in somatic tissues present in both males and females (Meisel 2011).

As mammals get older, telomeres progressively become shorter in many of their replicative somatic tissues and therefore likely contribute to the accumulation of senescent cells with advancing age (Zhu et al., 2011).