Sentence examples for many somatic DMRs from inspiring English sources

Many somatic DMRs are only allele specifically methylated in selected tissues - for example, GNAS 1A in brain, MEST isoform 2 in placenta [ 41], MKRN3 in liver and SLC22A1 in placenta - and our data confirms this.

Cancers with many somatic mutations rarely had many unusual copy numbers, and vice versa.

Our analysis contained both germline DMRs, such as the H19 ICR and somatic DMRs which acquire methylation after fertilisation, such as IGF2 DMR0.

Somatic DMRs are more variable in their methylation levels and are also likely to be tissue specific.

Most of the gene body DMRs were somatic DMRs.

Among the 29 DMRs analyzed, there were 20 gametic DMRs and 8 somatic DMRs.

Somatic DMRs also regulate the expression of the imprinted genes.

We also compared the frequencies of aberrant methylation between gametic DMRs and somatic DMRs.

DMRs can be sub-classified into germ-line and somatic DMRs.

This was also true for known paternally methylated somatic DMRs.

Overall, 11/43 DMRs had CTCF binding in liver and, of these, six were germ-line and five were somatic DMRs.