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Exact(6)
In addition, there could be many potential substrates that are not identified by our method.
Originally identified as a regulator of glycogen metabolism, GSK3 is a multifunctional serine/threonine kinase that has many potential substrates.
This specificity comes from their ability to negatively select against many potential substrates by virtue of the activation segment, a loop at the active site that creates a shallow hydrophobic pocket most compatible with the binding of proline [3], [4].
There are many potential substrates for Epe1.
If any of these genes is expressed and indeed codes for an isomerase like the Bombina enzyme, many potential substrates, such as hormones, neurotransmitters, antimicrobial peptides, etc. would be present in different cells.
The enzyme has a rather broad specificity, particularly with respect to the amino acid in position 2. A search in the databanks has shown that many potential substrates for such an isomerase are present in the skin secretions of other frogs as well as in mammalian cells.
Similar(53)
For some genes, this step eliminated many potential NMD substrates.
Currently, CaMPDB, an online repository of calpain sequences [37], lists a little over a hundred confirmed substrate sequences, along with a computationally expanded set of many thousands potential substrate candidates, obtained through BLAST alignment search.
The high degree of diversity of the mucin oligosaccharide chains provides many potential binding sites and metabolic substrates for bacteria, and is believed to be an important determinant in the site-specific colonization of commensal bacteria along the GI tract.
A large part of this secretome consists of the many extracellular hydrolytic enzymes necessary to digest potential substrates.
The homologous recombination (HR) pathway, one of the major pathways of DNA repair, includes many proteins, some of which may be potential substrates for BAP1-mediated ubiquitin hydrolysis.
Related(20)
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