Sentence examples for maintaining mitochondrial morphology from inspiring English sources

The ER mitochondria organizing network (ERMIONE) in Saccharomyces cerevisiae is involved in maintaining mitochondrial morphology and lipid homeostasis.

Collectively, these results suggest that Porin is important for maintaining mitochondrial morphology.

Controlling mitochondrial remodeling process is not only important for maintaining mitochondrial morphology but also for mitochondrial functions, which may determine the cellular activity and survival [17].

Recent studies have attributed several roles to LETM1, including maintaining mitochondrial morphology, mediating either calcium or potassium/proton antiports, and facilitating mitochondrial translation [ 9– 11].

These data suggest that Crif1 is important for maintaining mitochondrial morphology and that A β-induced mitochondrial disruption is mediated by attenuating Crif1 levels.

Mitochondria are highly dynamic that undergo continuous fission and fusion processes, which are important for maintaining mitochondrial morphology, distribution, and functions.

As a result, the engineered strain C-Fzo1 overexpressing mitofusin fzo1, which regulates mitochondrial fusion and maintains mitochondrial morphology, could effectively inhibit intracellular ROS formation and increase cell viability, and thus enhance cell tolerance during high levels of acetoin stress.

Studies in Drosophila have shown that the cytosolic E3 ubiquitin ligase parkin and the mitochondrial kinase PINK1 are involved in a pathway that maintains mitochondrial morphology where PINK1 is active upstream of parkin [8] [10].

This suggests that Pink1 and Parkin maintain mitochondrial morphology at least in part by preventing mitochondrial fusion or by enhancing mitochondrial fission [ 261].

IF-based P1b could either provide a scaffolding platform for proteins that establish and/or maintain mitochondrial morphology on the surface of the organelle (such as Mfn-2), or the interlinkage of mitochondria and IFs mediated by P1b may play a mechanical role in shaping the organelle.

Moreover, OPA1, by maintaining mitochondrial cristae morphology, has a direct metabolic effect, stabilizing respiratory chain supercomplexes (RCSs) (Cogliati et al., 2013).