Sentence examples for maintaining mitochondrial function from inspiring English sources

Taken together, these data identify Clu as a mitochondrially-associated protein that plays a direct role in maintaining mitochondrial function and that binds TOM20, and support a role for Clu linking mitochondrial function to the PINK1-Park pathway.

Conclusion: The results indicate that preterm fetuses are more capable than term fetuses of maintaining mitochondrial function under conditions of transient intrauterine ischemia and suggest that oxygenderived free radicals may play a crucial role in the development of neonatal neurologic deficit.

We examined the critical roles played by the antioxidant, non-protein thiol, glutathione and related enzyme, glutaredoxin in maintaining mitochondrial function during excitotoxicity caused by β-N-oxalyl amino-l-alanine (l-BOAA), the causative factor of neurolathyrism, a motor neuron disease involving the pyramidal system.

In other terms, the failure of maintaining mitochondrial function through biogenesis may contribute to bad outcome.

Our hypothesis is that cellular mechanisms maintaining mitochondrial function must be protected in order to prevent MODS.

Exposure of cells to estrogen upregulated Grx1 and prevented L-BOAA mediated loss of MMP clearly delineating the important role of Grx1 in maintaining mitochondrial function and thereby the cell viability.

As both enzymes are involved in maintaining mitochondrial functions, their increased expression after S 35171 treatment may be responsible for delaying the pathological condition that leads to the development of brain damage in SHRSPs.

Altogether, our results show that quercetin supplementation to 3-NP induced HD animals ameliorated mitochondrial dysfunctions, oxidative stress and neurobehavioral deficits in rats showing potential of this flavonoid in maintaining mitochondrial functions, suggesting a putative role of quercetin in HD management.

Formation and maintenance of the mitochondrial network play an important role in maintaining mitochondrial functions.

Mitochondrial chaperonins, such as HSP60, together with HSP10, refold all proteins imported into the mitochondrial matrix and facilitate the restoration of unfolded or misfolded matrix proteins under normal and stressed environments; hence, they are vital for maintaining mitochondrial functions, including ATP synthesis [ 2– 4].

We also demonstrate that Blm10 acts to maintain mitochondrial function.