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Thus, the carnitine shuttle system is considered to be a prominent factor in maintaining mitochondrial performance and glucose homeostasis.
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Mitochondrial dynamics refers to the processes maintaining mitochondrial homeostasis, including mitochondrial fission, fusion, transport, biogenesis, and mitophagy.
In other terms, the failure of maintaining mitochondrial function through biogenesis may contribute to bad outcome.
Cardiolipin (CL) has a critical role in maintaining mitochondrial inner membrane structure.
In eukaryotes, mitochondrial fusion-fission is important for maintaining mitochondrial numbers and morphology, and plays a critical role in sustaining functional mitochondria [32,33].
In the case of Parkinson's disease, many signposts point to disruption of mitochondrial health as a major factor and thus the importance of mitochondrial transport in maintaining mitochondrial health takes on great relevance.
Mammalian mitochondria have their own NAD biosynthetic machinery which plays a key role in maintaining mitochondrial NAD pool [13, 115].
The ER mitochondria organizing network (ERMIONE) in Saccharomyces cerevisiae is involved in maintaining mitochondrial morphology and lipid homeostasis.
This report highlights a novel function of PINK1 in mitochondrial biogenesis and a role in maintaining mitochondrial ETC activity.
Controlling mitochondrial remodeling process is not only important for maintaining mitochondrial morphology but also for mitochondrial functions, which may determine the cellular activity and survival [17].
Collectively, these results suggest that Porin is important for maintaining mitochondrial morphology.
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