Sentence examples for main effector cell from inspiring English sources

CD8+ cytotoxic lymphocytes (CTLs) are known to be the main effector cell in viral infection [ 6].

Thus, the myofibroblast is widely considered the main effector cell of fibrosis and thereby a major therapeutic target.

FLS is a main effector cell type in the progression of RA, promoting pannus formation with cartilage erosion and progressive joint destruction by secreting diverse cytokines, chemokines, and MMPs [ 5, 8, 9].

B16FasL were selected for the following reasons: i) B16FasL, as opposed to B16F10, is rejected in RAG /– mice as efficiently as in B6 mice; ii) the innate immune response to B16FasL is sufficient to reject the tumour (Fig. 1); iii) we have identified NK cells as the main effector cell type mediating this innate B16FasL immunity in both B6 and RAG /– mice.

We observed no expression enrichment of CeD genes in any of the cell types tested, suggesting that the main effector cell type involved in the pathophysiology of CeD might not have been represented by the cell types present in our panel of cells.

CD8+ T cells are the main effector cells responsible for viral clearance as well as disease pathogenesis during HBV infection (Thimme et al., 2003; Harari et al., 2006; Ouyang et al., 2013).

Whereas CTLs are traditionally thought to be the main effector cells that eliminate HCV-infected cells [5], it is clear that HCV-specific CD4+ T cells also play a critical role.

During the early stages of infection with intracellular pathogens like M. tuberculosis, the extent of bacterial survival and proliferation is mainly determined by the efficacy of the innate immune response with macrophages as the main effector cells [13], [14].

Hepatic stellate cells (HSC) are the main effector cells for liver fibrosis.

Hepatic stellate cells (HSC) are the main effector cells in liver fibrosis [ 1].

Lymphocytes are the main effector cells of the immune system [ 38].