Sentence examples for primary effector cell from inspiring English sources

The primary effector cell in fibrosis is the myofibroblast; these cells are highly synthetic for collagen, have a contractile phenotype, and are characterized by the presence of α-smooth muscle actin stress fibers.

Although CD4+ T cells are considered the primary effector cell in protective immunity, the role of CD8+ T cells in protection from respiratory infection with A. fumigatus remains unknown.

The proportion of genes in a particular cell type that can be detected in a cell mixture might be lower for target cells comprising a smaller proportion of the mixture or in which the cell type of interest is not the principal target or primary effector cell.

The α7R is expressed by leucocytes; however, macrophages have been identified as the primary effector cell [ 22].

However, innate immune cells such as macrophages play a key role and are likely the primary effector cell in the killing and ultimate clearance of cryptococcal infection.

Exposure to free silica induces silicosis and myofibroblasts are regarded as primary effector cells.

Classic ADCC assays measure antibody-dependent target cell cytotoxicity induced by primary effector cells that are isolated from human blood.

Our results also show that engineered NK or reporter cell lines provide reduced variability compared to primary effector cells for in vitro ADCC assays.

However, reproducible quantitation of ADCC activity on a cellular level remains highly challenging, as ADCC assays rely on primary effector cells associated with laborious cell purification procedures, resulting in highly donor-dependent results.

GBS, however, results from macrophages serving as the primary effector cells in the demyelination of the peripheral nervous system.

Surprisingly, we found that the expanded memory cell population also expressed a higher level of Notch receptors than primary effector cells.