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In view of the rapid changes in genotyping technologies and costs, breeding programs based on genomic selection need to be re-evaluated and optimized on a regular basis.
As a sustainable alternative to vaccination, we have been pursuing a strategy of identifying chickens with enhanced genetic resistance to MD based on genomic selection (GS) for breeding naturally MD resistant flocks [ 8].
This study proposes a new paradigm, where based on genomic selection of tumour types, the fusion protein Antp-p21 can act on its own and also enhance the efficacy of chemotherapy leading to tumour eradication in p53- or p21-mutated tumours.
Because the accuracy of genomic EBV established in the reference population, r g g ˆ 0 refers to the accuracy in a population that is not under selection, there is a distinction between r g g ˆ 0 and the Bulmer equilibrium accuracy of a breeding scheme based on genomic selection, denoted r g g ˆ e q. in this paper.
Allele frequency of the 20 QTN with the largest effect that still segregated in generation 0 across 21 generations of recent historical breeding based on genomic selection only (GS only) and 20 generations of future breeding based on GS only or genomic selection plus the promotion of alleles by genome editing (GS + PAGE) when 1, 5, or 10 QTN were edited for all 25 selected sires.
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The population was split into two sub-lines, one was submitted to conventional phenotypic selection, and one was selected based on genomic prediction.
Genomic selection refers to selection decisions based on genomic estimated breeding values (GEBV) [ 1].
The average bias and MSE are presented in Table 4 for YS and in Table 5 for their daughters for different combinations of trait heritability and genomic pre-selection intensity levels and when selection based on genomic information is fully (GPS_all) or not accounted for (GPS_no).
Selection based on genomic estimated breeding values (GEBV) for purebreds (PB) using phenotypes on crossbreds (CB) is expected to increase the response to selection observed in CB compared to the situation in which only PB phenotypes are used.
However, selection based on genomic information could be a promising alternative [ 4].
Therefore, selection based on genomic information could be an interesting alternative [ 10].
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based on genomic screening
based on genetic selection
based on gene selection
based on dna selection
based on genomic instability
based on certain selection
based on genomic correlation
based on genomic expression
based on genomic position
based on magnetic selection
based on genomic sequence
based on backward selection
based on sexual selection
based on genomic context
based on genomic survey
based on random selection
based on genomic diversity
based on genomic understanding
based on genomic variation
based on natural selection
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