Sentence examples for based on gene selection from inspiring English sources

Additionally, PGR, TBC1D9, and NAT1, which were found to be important predictors based on gene selection using LASSO, were not included in either backwards elimination model.

Based on gene selection criteria (p < 0.05 and ≥2-fold change), BCL-2 was up-regulated by 20-fold and 13 genes were down-regulated by ≥2-fold in chemoresistant Skpac cells, compared to parental SKOV3 cells (supplementary data Table S6).

Moreover, in order to select the most informative genes, we propose to perform feature selection via additively optimizing a nonparametric margin maximum criterion, which is defined based on gene pre-selection and sample clustering.

We define this criterion based on gene pre-selection and sample clustering to make it robust to noise and outliers.

The identification of these genes will provide insight on disease pathways and resistance mechanisms, leading to more effective vaccines or other control strategies, and even more effective selection schemes based on gene-assisted selection [ 11].

Their primary objective is to discriminate patients into subgroups with different survival profiles based on gene expression data, that is, selection of relevant gene subsets associated with prognosis for the whole study population regardless of specific subpopulation characteristics.

However, the traditional pathogenicity genes selection methods based on gene expression data treat each gene individually and interaction between them is not considered.

The networkScreening function in the WGCNA R package computes the gene selection score p.weighted based on gene significance and on module membership [ 45].

Similarly, Figure 5B shows that the variances of the gene substitution effects are reduced at the higher frequencies of allele 1. Traditional selection based on gene substitution effect has a low or no pressure on a major gene segregating in a population where the major gene exhibits non-additive variation and the favorable allele is found at a low frequency - as explained by Dodds et al. [ 39].

GC and MF designed variable selection method based on gene co-expression and built UniHi db.

Our failure to identify a good marker of oncocytoma is not surprising, as marker selection was based on gene expression differences between ccRCC and chRCC only and the genetic profiles of oncocytoma and chRCC appear to be remarkably similar[ 64].