Sentence examples for which subsequently activated from inspiring English sources

Activation of Raf resulted in the phosphorylation and activation of MAPK kinase (MEK1) which subsequently activated ERKs.

However, in conjunction with previous results in Bm1 BMCs (Fig. 1C), it is possible that peptide antigens from the injected peptide-DCs were transferred to cell types other than CD11c+ DCs, which subsequently activated naïve CD8+ T cells.

These results suggested that glucose promoted the expression of AREG, which subsequently activated HIF-1 and induces the expression of GLUT1.

The above in vitro data suggested that the stimulation of soluble factors derived from T cells might be the main cause of TLR3 upregulation, which subsequently activated FLSs, although we still could not rule out the role of cell contact.

In vitro studies demonstrated that elevated H2O2, generated by hepatocytes expressing CYP2E1 increased the intracellular concentration of H2O2 in HSCs, which subsequently activated HSCs and induced collagen I production [ 16, 17].

The role of p53 and DAPK in natural product-induced autophagy is not fully revealed, but Wang et al. found that fangchinoline could lead to nuclear translocation of p53, which subsequently activated sestrin2 transcription and initiated autophagic cell death in HCC [ 40].

Insulin signaling is initiated by the binding of insulin to the insulin receptor to activate IRS-1, which subsequently activates PI3K; the activation of PI3K results in the recruitment of GLUT4 to the cell surface [ 17].

When cells are challenged with replication stress, single stranded DNA coated with RPA becomes exposed due to a decoupling of the helicase and polymerase activities at the replication fork: this is the substrate for ATR recruitment and activation, which subsequently activates Chk1 kinase.

Trapping enhancer elements using the gene for the activator Gal4, which subsequently activates a reporter such as lacZ (possessing a Gal4 UAS), has been very successful in yeast and Drosophila [ 10].

Several reports demonstrate that acupuncture may suppress seizure activity through the activation of vagus nerve, which subsequently activates the nucleus of tractus solitarius (NTS) [ 7, 8].

Activation of Rip2 recruits and activates the TAK1 (TGFβ-activating kinase1 -TAB2-TAB3 complex, which subsequently activates the IKK complex and MAPK pathways (Caruso et al., 2014; Yang et al., 2007).