Sentence examples for which once activated from inspiring English sources
Mutant p53 was also shown to induce the expression levels of the insulin-like growth factor I receptor gene (IGF1R (111)), which once activated is able to trigger both phosphatidylinositol 3-kinase (PI3K /AKT and Ras/mitogen-activated protein kinase (MAPK) prosurvival pathways, often deregulated in breast cancer (112).
What seems to trigger this is an internal risk sensor, which, once activated, causes him to become overwhelmingly cautious.
Each of the two recorders has a beacon, attached to the outside of the black box, which once activated by contact with water makes a sound every second.
Moesin is the sole Drosophila member of the ERM proteins, which, once activated via phosphorylation, crosslink actin filaments to the cytoplasmic tails of plasma membrane proteins.
A "dropper" program named "INPEnhSetup.exe" posed as a Windows installer, which once activated contacted a server across the internet – a domain owned and operated by Xunlei - and "dropped" or installed three further malicious programs onto the system.
DC can prime and induce proliferation of NK cells, which, once activated, acquire the ability to kill immature DC (iDC), through engagement of the activating receptor NKp30, and may also induce DC maturation [5], [6].
Peptides from intracellular pathogens proliferating in the cytoplasm are carried to the cell surface by MHC class I molecules and presented to cytotoxic (CD8+) T lymphocytes, which once fully activated have the capacity to lyse infected target cells.
High PARP1 activity results in autoPARylation of PARP1 in the enzyme's automodification domain, which would mean that once activated, PARP1 shuts itself off automatically and then requires PARG for reactivation.
Once activated, Sirt-1, which is an NAD-dependent HDAC, can deacetylate essential autophagic modulators and may affect cellular pathways involved in glucose homeostasis.
Once activated, PMNs release ROS, which contributes to oxidative stress and the inflammation and endothelial damage that follow.
Once activated, IKKβ phosphorylates IκBα, which undergoes ubiquitination and proteasomal degradation, allowing NF-κB phosphorylation and nuclear translocation.
