The second scene of Mr. Burns, a Post-Electric Play takes place five years after the United States has suffered a massive electrical failure which subsequently triggered meltdowns at America's nuclear power plants.
Previous studies have shown that enhanced [Ca2+]i mediated by InsP3R and RyRs increased sequestration of vast amounts of Ca2+ in mitochondria ([Ca2+]mito), which subsequently triggered mitochondrial membrane permeabilization and led to apoptotic cell death.
It was shown to reactivate the p53 pathway of the cells with wild type p53 by inducing the transcription of its downstream targets, p21 and MDM2, alongside the proapoptotic genes, PUMA, Bax, and Bak, which subsequently triggered cell death [ 58, 59].
Upon NIR light irradiation, GO converts absorbed light into heat, which subsequently triggers the shrinkage of PANIPAM chains, leading to the bending of the bilayer actuator.
Local corrosion is triggered at anodic β-phase precipitates proximate to the constituent particles, which subsequently triggers the corrosion of un-attacked β-phase precipitates often aligned on grain boundaries.
In these cases, the problem is not only hemorrhage, but also the multiple tissue injuries associated with prolonged shock, due to both hypovolemia as well as alveolar and tissue hypoxia, which subsequently trigger a hyperinflammatory response [16, 17].
It was concluded that the exposure of sexually inactive bucks to goats in oestrus is an inexpensive, practical and efficient way to elicit sexual activity in bucks, which subsequently triggers breeding activity of anoestrus French Alpine goats.
Once the changes in voltage is sensed by the VSDs, these domains experience large-scale conformational change among the resting, active and inactive states, which subsequently triggers the PD structure to transit between the open and closed states (Hodgkin and Huxley, 1952; Isacoff et al., 2013).
Reports from our own group and others demonstrated that HDACIs can induce DNA damage [7], [38], which subsequently triggers apoptosis in leukemia cells.
Taken together, these results imply that stretch of mdx muscle produces ROS, by activation of NADPH oxidase, which subsequently triggers Ca2+ entry through SAC leading to muscle damage and contractile dysfunction.
We see that the cell switches its expression pattern from a high-Ptf1a to a high-Ngn3 pattern which subsequently triggers the cell to go through the Pax4-Arx branch point to finally reach the steady state of the beta cell.
