Sentence examples for true mutation from inspiring English sources

Thus synonymous substitution rates are probably very close to the true mutation rates of neighbouring non-synonymous sites that accumulate the actual mutational damage.

This low rate of true mutation, 7%, is similar to the mitochondrial HVI mutation rate reported using other methods [29].

It is extremely unlikely that any of the sequence changes that we scored as a "true" mutation was due to a PCR amplification error.

The immune escape mutation (as a consequence of a true mutation or a re-assortment [19]) generates a new antigenic cluster called the mutant.

So, it remains unclear whether this is a true mutation or a rare polymorphism.

For these reasons, CDR3 is susceptible to having its true mutation rate underestimated.

By tagging each starting molecule with a unique identifier, Safe-SeqS enables researchers to differentiate true mutations from procedural artifacts.

The number of false-positive calls is also markedly reduced (>10-fold), and our panel design allows for distinction between true mutations and deamination artifacts.

Incorporating molecular barcodes, also known as unique molecular indices or UMIs, may prove useful for improving efficiency and distinguishing true mutations from PCR or sequencing errors [27].

Thus, two of twenty-eight hair shaft sequences were scored as true mutations.

We have chosen to define true mutations based on a conservative interpretation of the data.