Sentence examples for genuine mutation from inspiring English sources

I see this work as a genuine mutation, a natural response to the displacement of bricks and mortar by virtual space.

Five cross-reactivity signals had Rm/Rwt>0.7, but in these cases, the assay for the genuine mutation had Rm/Rwt>1.0.

In both of the experiments, numerous low-frequency variants were detected by sequencing, and it could not be determined with certainty in the case of a given variant whether it represented a genuine mutation or a sequencing artifact.

Two major computational steps in variant detection from NGS data are read alignment whereby the data are mapped to corresponding locations on a target genome, and mutation calling whereby nucleotides differing from the target genome are assessed and scored on their likelihood of representing a genuine mutation versus an error.

However, even if only a minority of such predictions is genuinely somatic, using only one program could potentially miss many genuine mutations.

Consequently, when a mis-incorporation occurs, it forms a mismatch following DNA amplification and is distinguished from genuine mutations that remain fully matched [89].

These methods may include, but are not limited to, physical separation which may apply the use of metals to chelate partially denatured purine bases and allow elimination of errors [88] or PCR-based approaches such as hairpin PCR, which completely separates genuine mutations from polymerase mis-incorporations.

Although the percentage of genuine mutations identified by 'Maq' and 'galign' is similar, the absolute number of true polymorphisms predicted uniquely be 'galign' may be over 3.5× more than predicted by 'Maq' under the assay conditions.

Hence these were not considered to be genuine mutations.

We then developed a strategy to identify the small minority of genuine mutations.

These base changes were therefore considered to be due to PCR errors and not genuine mutations.