Sentence examples for accurate mutation from inspiring English sources

In conclusion, NeuroX appears to be helpful for rapid and accurate mutation screening, although further development may be still required to improve some current caveats.

To develop an accurate mutation analysis procedure for retinoblastoma gene (RB1) mutation, which is sensitive at the single-cell level, and to use in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD) to achieve pregnancies without retinoblastoma.

b The Sanger's sequencing provides accurate mutation information: In exon 19, NCI-H1650 cells show a deletion mutation (Del E746-A750); in exon 20, NCI-H1975 cells show a point mutation (T790M); in exon 21, NCI-H1975 cells show a point mutation (L858R).

Together, these observations suggest a rapidly growing need for sensitive and accurate mutation detection in clinical specimens as part of routine clinical care.

Contrarily, having too few mutants will not provide an accurate mutation spectrum.

To obtain more accurate mutation rates in both PbCtl and PbMut, mutation rates from several lineages would be required.

This current study provides more accurate BRCA2 mutation frequencies for PrCa cases and relative and absolute PrCa risk estimates for BRCA2 mutation carriers.

While many techniques have emerged over the past few years to match the ever-growing need to provide accurate clinical mutation analyses to oncologists, none of these have been systematically benchmarked against massively parallel sequencing, the method with the highest sensitivity for clinical mutation detection to date.

This retrospective study demonstrated accurate PIK3CA mutation detection in plasma using ddPCR in patients with early‐stage TNBC.

The availability of existing mutations will enable more accurate assessments of mutation frequency such as noncomplementation screens (Greenwald and Horvitz 1980).

We next performed a more sensitive breakpoint genotyping step in order to exclude germline SV breakpoints that may have been misclassified as somatic mutations due to inadequate coverage in the diploid (D) sample, and to obtain more accurate patterns of mutation sharing among the tumor subpopulations.