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For example, elucidating the evolutionary history and global spread of bacterial pathogens requires robust strain assignment [1].

However, because of the inherent phylogenetic limitations of these tools, final strain assignment to specific strain lineages should be based on more robust markers such as SNPs or LSPs.

Strain assignment, morphospecies, origin and accession number in GenBank are given when available.

Alland et al. [ 37] proposed instead a set of nine SNPs that allowed strain assignment to any SCG and each subgroup [ 37].

The 4 hypervariable regions within the 56-kDa type-specific antigen of O. tsutsugamushi, which is located on the outer membrane surface, are considered to play an essential role in type strain assignment (2 ).

Similar(55)

Ensembl v41 (October 2006) includes amino acid strain assignments for missense SNPs and should allow us to correct this deficit.

The strain-haplotype pattern for the single significantly associated block B7 consists of five haplotypes with the mouse strain assignments shown in Table 3.

Mcvq4 included the well-studied hemoglobin β (Hbb) locus that has a demonstrated effect on MCV (Kano and Nishida 1972), and the estimated QTL allele effects matched the previously reported strain assignments of the Hbb single (s; C57BL/6J, NOD/ShiLtJ, and NZO/H1LtJ) and diffuse (d; 129S1/SvImJ, A/J, Cast/EiJ, PWK/PhJ and WSB/EiJ) alleles (Erhart et al. 1985; Gilman 1976; Popp et al. 1982).

Although calculations of ΔK do not allow for differentiation between one or two groups in the dataset, the strains' assignment (Table 2) was most congruent with the existence of two sub-populations.

Strain population assignment was performed as described by Falush et al [7], using the "no admixture" model in STRUCTURE2.0 [31], the proportion of nucleotides being derived from ancestral population was estimated using the "linkage" model in Structure2.0 as described [7], [26].

Our goal is to efficiently assign taxonomic labels to the reads down to the species level for reads with reference representation and maintain accuracy in the presence of novel organisms by avoiding overly specific (e.g. species and strain) taxonomic assignments.

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