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Alterations of bone material level properties caused by a low protein diet could increase propensity to damage accumulation during cyclic mechanical loading.
In principle, the dinucleotide mutations observed in breast cancer could also be due to exposures with a propensity to damage adjacent DNA bases.
Leptospirosis is a common cause of acute tubulointerstitial nephritis that may cause acute kidney injury, and it has the propensity to damage blood vessels and the kidney structure.
Reports of benzene's propensity to damage human blood-forming tissues emerged as early as 1897 (Santesson 1897), and the first evidence of its leukemogenicity was published in 1928 (Delore and Borgomano 1928).
In the present study, the degradation of parameters reflecting plastic behavior in rats fed a low protein diet after cyclic loading could be explained by an alteration of bone material level properties, leading potentially to an increased propensity to damage accumulation.
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As expected, the cooling is reflected in an increased stiffness of tested specimens and their higher propensity to the damage.
Might the secretory ability of cells within the female reproductive system be linked to their reported high propensity to DNA damage, and so directly mediate their contribution to ovarian cancer?
We have characterized fatty acid metabolism in detail in vivo using stable isotope tracers in mice fed CDD and MCDD and identified pathways that could explain contrasting propensity to hepatocyte damage and steatohepatitis in these models, observations with implications for understanding the pathogenesis of human NASH.
We modelled this by including an additional species UCHL1_mut to represent the I93M mutant and assumed that this had a higher propensity to become damaged.
For the I93M mutation we assumed that either the mutant had lower hydrolase activity than wild-type or that in addition the I93M mutant had a greater propensity to be damaged.
These new blood vessels are weak and have a propensity to leak, damaging the retinal cells and leading to scar tissue.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com