Sentence examples for mutations will affect from inspiring English sources

But how much such mutations will affect the ability of the virus to cause disease cannot be determined now, Dr. Heymann said.

In designing mutagenesis experiments, it is often crucial to know how certain mutations will affect the structure and thermodynamic stability of the protein.

Under the conditions of mutation-selection equilibrium, fitness interactions between mutations will affect the frequency of individual mutants within a virus population.

It is known that DNA mutations will affect gene expression.

Patient-specific mutations will affect some or many of a diverse array of protein interaction partners.

Mitochondrial mutations result in pleiotrophic effects and possibly, different mutations will affect the aging rate differently and in a tissue specific manner.

Thus any alterations in APP protein and in its metabolites almost certainly reflect an effect of the YG mutation on the fate of the APP protein, since it is very unlikely that the point mutation will affect the translational efficiency of the KI mRNA.

So while it may be impossible to know exactly how any specific mutation will affect a given activity, measuring a handful of activities may allow one to make relatively accurate predictions about other closely linked activities [ 47].

The second determinant will be the timing when the trigger hits its target: an early hit during vasculogenesis (such as a germinal mutation) will affect more cells and will lead to a metamerically arranged defect, whereas a late hit (such as a somatic mutation that occurs late during the fetal life or even postnatally) will have a more focal impact on the vessel [ 3].

Since CD44 contributes much to BCICs' maintenance and activity as its surface marker and BCICs play an important role in breast cancer tumorigenesis, it is inferable that the possible quantitative change of CD44 caused by rs13347 C/T mutation will affect breast cancer development, especially in ER-negative patients.

Transverse mutations are much less frequent than the transition mutations and will affect these equations to a smaller extent.