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Development of fibrosis and/or cirrhosis plus a microenvironment conducive to genomic instability mutations will promote neoplastic transformation.
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In other words, saeptation will be the consequence of a mutation that will promote increased inbreeding within a group inheriting that mutation, and thus in a reduction of the gene flow between this new group and its immediate ancestral stock.
We expect that natural selection will promote those mutations that alter the antigenic character of the virus without causing loss of function of the HA and NA proteins.
Positive epistasis will promote the evolution of resistance, because successive resistance mutations will incur diminishing costs; if epistasis is strongly positive, it is even conceivable that strains carrying multiple mutations that are individually costly may even pay no cost for resistance.
This would support our hypothesis that LARS2 itself has a stabilising effect on the tRNA substrate, which in turn will promote more efficient aminoacylation, particularly in the case of destabilizing mutations.
That will promote daddishness.
Tells about how Random House will promote it.
The fund will promote civil liberties.
I will promote adoption.
We will promote our values; we'll promote the peace.
"We will promote individual choice.
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