Sentence examples for mutations which resulted from inspiring English sources

The sequence analysis revealed a total of 16 point mutations which resulted in amino acids substitutions across the three genotypes (Table 4).

We filtered the complete set of mutagenesis data from SWISS-PROT release 56 for single amino acid substitution mutations, which resulted in a dataset containing 20787 mutations.

The other two lines, designated 165 and 397, contained mutations which resulted in missense amino acid changes[ 23].

Finally, the four consensus candidate mutations, which resulted as the best replacements of the WT sequence, were expressed, and characterized by SPR, CD, and thermal-based shift assay.

Twenty-two tumours had insertion/deletion mutations, which resulted in a frameshift, and one tumour had an in-frame deletion located within the STAG domain.

The synergistic effect of the two mutations, which resulted in a laccase enzyme with higher activity and strongly improved functional expression was not foreseen by the homology model.

IL-6 levels are elevated in lung cancer patients in cells lines with endothelial growth factor receptor (EGFR) mutations which results in STAT3 elevation [110].

The CIP patients, characterized by lack of nociceptive perception, are mostly inflicted by Nav1.7 nonsense mutations, which result in premature protein truncations and inability to produce functional sodium channels.

This observation is expected because indels in coding regions can lead to frameshift mutations, which result in a truncated protein that may be hyper-, hypor, or neomophic explaining the high negative selective pressure in coding regions.

One out of billions of cells acquires a mutation, or several mutations

Most GBA mutations are missense mutations, which result in a misfolded protein.