These risk calculators, and the task force's measured recommendations, do not apply to women who have the BRCA-1 or BRCA-2 gene mutations, which confer an extremely high risk of developing breast cancer, and they don't apply to women younger than 35 or older than 79.
Thus, the mutations which confer the fluorescent phenotype are point mutations of the TAG stop codon.
These have identified genetic mutations which confer either hypersensitivity or resistance to ethanol.
In general, the mutations which confer resistance to the largest number of drugs in the combination are the ones which define how likely it is that the protocol fails.
The lethal phenotype caused by injection of young w1118 males with 3×104 TCID50 at 25°C was robust and sensitive enough to be used an assay for the identification of mutations which confer increased susceptibility or resistance to CrPV infection.
Furthermore, US isolates had unique mutations which confer high-level resistance to ceftriaxone and have been associated with other ST.
It proposed that environmental conditions trigger non-specific mutations which confer adaptation to the stress-inducing factors [ 59].
Therefore, the K298E mutation becomes another member of a small group of exon 10 mutations, which confer pathogenicity through effects at both the RNA and the protein level.
In order to become malignant cancer cells, normal cells need to acquire a set of mutations which confer "hallmark" traits, such as increased proliferation, immortality, and invasiveness [ 2].
In the present study, 94% of INH resistances, close to the high limit of reported range, were attributed to katG mutations which confer high level resistance to INH.
