Sentence examples for mutations which had from inspiring English sources
In contrast to the clustered mutations, which had the same mutational APOBEC signature as the top strand lesions, the unclustered mutations show less of a preference towards mutating the C of TpC, most evident for those induced by restoration of T/G to C/G (cf. lower 2 panels, Figure 5A and the lower panels labeled unclustered, Figure 5B).
Only the mutations which had a 10 fold affinity over the normal peptide were called as neoantigen.
The silent mutations, which had shown association with reproductive seasonality in other breeds, were also found and genotyped in Rasa Aragonesa.
On further investigation, the scientists found that two other mutations, which had negligible effects by themselves, strengthened some of the protein's folds so it could withstand the other five mutations.
Recently, cortical sparing adrenalectomy in patients with RET or VHL mutations which had low risk of malignant PPGL has been reported [12, 13].
In the three patients studied here, the M154L and V165I mutations, which had been associated with previous antiretroviral experience [11], were not present at baseline.
BRAF-mutated melanoma contain a lot of additional mutations which have been shown to overcome the effects of BRAF (and MEK) inhibitors and lead to a primary resistance to the drug (reviewed by Shtivelman et al).
These observations highlight the importance of kinetic binding analysis for studying disease-associated HIF-2α mutations, which has not been previously reported.
The influence of advancing maturity on degradabilities was greater for wx1, su2 and Oh43, than for o2 and fl2 mutations which have inherently soft endosperm properties.
That way, any mutations which have arisen during DNA replication will not affect the all-important stem cell population.In this section Wild East or scientific feast?
Janus Kinase 2 (JAK2) gene single point mutations, which have been reported to be associated with myeloproliferative disorders, are usually detected through conventional methods such as melting curve assays, allele-specific and quantitative Polymerase Chain Reactions (PCRs).
