Sentence examples for mutations was highly from inspiring English sources

During the development of the KeyPoint technology, we noticed that the number of sequence changes compared to the wild type sequence, which reflects the combined total of PCR- and sequence errors and genuine EMS mutations, was highly variable across all positions of the amplicon sequence.

Thus, gefitinib chemotherapy in patients with advanced NSCLC harbouring EGFR mutations was highly effective.

Each of the mutations was highly beneficial, regardless of whether the mutation arose in that host during evolution.

As previously reported, the phenotype of the patients with PCDH19 mutations was highly variable between families but also within affected members of a same family (Table 2).

The results showed that GNAS mutations were present in a rather organ-specific manner, whereas the prevalence of KRAS mutations was highly variable among each type of tumours.

Mutational frequency and type of somatic point mutations were highly variable among the different MPNSTs modeled, but very consistent when comparing primary tumors with matched orthoxenografts generated.

She and other women with BRCA1 or 2 mutations are highly likely to develop breast cancer at some point in their lives.

The explanation of this phenomenon is that dark moths, which originally were chance mutations, were highly visible to predators when resting on lichen-covered trees during the day.

It also adds that somatic de novo mutations are highly variable, may depend on tissue and age of the individual, and could add to predisposition for disease.

In particular, the distribution of mutations is highly associated with intrinsic molecular processes including transcription, chromatin organization, DNA replication timing, and DNA repair.

Genetic diagnosis in HHT is difficult, as mutations occur in numerous different locations in the linked genes, without particular mutations being highly frequent (as opposed to, for instance, the ΔF508 mutation in cystic fibrosis).