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A meta-analysis based on the interpretation of published data from 159 patients carrying 40 different heterozygous desmin mutations provided highly valuable insights into this complex issue [ 183].
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We included only nGGO specimens resected en bloc to ensure sufficient tumor cell sampling; this is the main strength of this study, as it provided highly accurate DS detection of EGFR mutations.
The different methods provided highly correlated data.
SSR loci provided highly informative markers.
Gene duplication mutations provided raw material.
AmyloidMutants is sensitive enough to distinguish dramatic shifts from one amyloid conformation to another when as little as a single point mutation is made; at the same time, it provides highly accurate predictions of structure, strain conformations and mutant amyloidogenicity.
ELISA, western blotting and IHC potentially provide highly specific protein detection but those mutations, insertions and/or deletions are not readily detected.
The genome-scale maps of the raIS elements in this work provide highly informative data for studying the distributions of IS elements and how they incur recombination mutations to the host genomes, which represents the next step of our study.
The actuator provides highly accurate position control.
Thus, this result highly suggests that the low alteration of the protein by point mutations providing resistance is the main driving force responsible for the maintenance of resistant alleles in natural populations.
Compared to genetic mutations, epigenetic mutations provide much faster responses.
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CEO of Professional Science Editing for Scientists @ prosciediting.com