Sentence examples for mutations is variable from inspiring English sources

The frequency of the discovered somatic mutations is variable and the alterations are heterogeneous, encompassing single nucleotide variations, small and large insertion/deletion events, structural rearrangements, and copy number variations.

Hearing impairment in patients with dRTA related to either ATP6V0A4 or ATP6V1B1 mutations is variable both in terms of onset and severity.

Due to these founder effects as well as due to other environmental and geographical factors, the prevalence of BRCA1 and BRCA2 mutations is variable among different populations [ 15].

The observations suggest that the clinical presentation of patients with dominant inactivating ABCC8 missense mutations is variable, ranging from mild medically responsive to severe early-onset CHI requiring a near total pancreatectomy.

55, 119– 123 Those with deletion tend to be shorter and lighter than the general population, while those with UPD or imprinting defects tend to be taller and heavier; growth in those with UBE3A mutations is variable.

12 Resistance to lamivudine and nevirapine is already present in 90% of patients by the time of virological failure, 39 40 but the rate of development of thymidine analogue mutations is variable.

The levels of resistance conferred by specific mutations are variable, ranging from insignificant resistance to triple-drug resistance.

However, the cytotoxicity from 2 patients with unknown genetic mutations was variable; moderately impaired in one (UPN30), and deficient in the other (UPN31).

Therefore, we can conclude that mutations are variable in their general mixing ability.

This analysis compares the number of S and NS substitutions by creating a neighbor-joining tree based on dN values (NS substitutions per NS site) and then determining whether mutations are variable (occur more than once in the tree) or invariable (occur in only one branch of the tree).

The phenotype associated with the Arg117His mutation is variable, depending on the other CFTR mutation present and the presence of a polypyrimidine variant in the intron 8 acceptor splice site; the mutation is often associated with less severe clinical problems [ 52].