Sentence examples for mutations is difficult from inspiring English sources

The number of people affected by mitochondrial mutations is difficult to calculate, since resulting conditions are varied and have divergent symptoms.

The effect of removing cysteines 6 and 111 on the yield of amyloid, even in the absence of ALS mutations, is difficult to explain; the replacement of these two cysteines may either cause some destabilization of the tertiary structure of SOD1 [42] or promote the formation of amyloid instead of other types of aggregates, like amorphous aggregates.

The actual prevalence of CDKN2A mutations is difficult to quantify.

Inferring the exact functional alterations of the human-specific and great-ape-specific mutations is difficult.

For such regions, the identification of mutations is difficult by using the short-read sequencing technology.

This dramatic difference in explanations for the embryonic lethality 'rescue' of these similar Brca1 mutations is difficult to reconcile.

These mutations were difficult to find in DNA at first because they were not located in the part of the gene that encodes the protein.

In kiwifruit, artificially generated mutations are difficult to generate and screen and genetic transformation is a difficult and lengthy process.

First, we uphold our opinion that experiments involving a large number of unknown mutations are difficult to interpret.

Because the functional effects of missense mutations are difficult to predict, a quick yet systematic approach to screen and prioritize human gene variants for subsequent testing in mammalian models is of great value.

It has been shown by several groups that gliomas with IDH1 mutations are difficult, if not impossible, to culture and propagate in vitro under standard serum-free or serum-containing culture conditions [ 38- 40].