Sentence examples for mutations is uncertain from inspiring English sources

The significance of uncommon mutations is uncertain.

The pathophysiology of olfactory identification loss in both nonmutation PD and related to LRRK2 G2019S mutations is uncertain.

The neuropathological spectrum of PD brains harboring VPS35 mutations is uncertain since no mutation carriers have yet come to autopsy (9).

Even though the biological significance of missense and silent mutations are uncertain, the mutational spectra of the APC gene may provide a more complete picture of impact and type of carcinogenic exposure.

It is believed that reverse mutations to subtype consensus are widely observed during the early phase of HIV-1 infection [2], [13], [15], [18], [19], although quantitative and timing relationships between reverse and escape mutations are uncertain.

One previously published case (Patient 12, Fratter et al., 2011) was omitted from the current analysis, as the pathogenic nature of the reported heterozygous mutation was uncertain after segregation studies.

How AGPAT2 and LPIN1 mutations cause lipodystrophy is uncertain.

The mechanism whereby germline SDHB mutations promote tumorigenesis is uncertain.

The importance of the mutation for this patient is uncertain, as hMYH mutations associated with colon cancer are autosomal recessive.

KRAS mutation testing is required to select patients with metastatic colorectal cancer (CRC) to receive anti-epidermal growth factor receptor antibodies, but the optimal KRAS mutation test method is uncertain.

Various forces contribute to heteroplasmy, but the extent to which heteroplasmies are inherited or arise via new mutations is still uncertain, making the study of heteroplasmy in the extreme elderly even more pertinent.