Sentence examples for mutation which generates from inspiring English sources

The functional consequence of hypertonia-associated Trak1 mutation, which generates a Trak1 mutant protein truncated at amino acid 824 (Fig. 3A), remains unknown.

Three of the complementing dpolv mutants in exon 11 are missense mutations but the complementing mutant dpolv105A is due to a nonsense mutation, and dpolv6 in exon 15 on the other side of the PIGSFEAST exon is a frameshift mutation which generates a stop codon.

Similarly, mouse models with the Osaka mutation, which generates oligomeric, but not fibrillar amyloid, develop synapse loss [ 200].

For instance, in the standard account evolutionary change begins with genetic mutation, which generates phenotypic differences that are subject to selection.

The deletion of a single guanine residue at codon 1524 within exon 34 produces a frameshift mutation, which generates a stop codon at codon 1566 (p.Gly1524Glufs∗42) and results in a premature termination codon.

The minimum change required for every new band in a tumor DNA, compared to its corresponding leucocyte DNA (referred to as 'gain' in this paper) would be one mutation, which generates a perfect match, creating a primer binding site.

However, we are primarily interested in adaptive processes under linkage in the dense-sweep regime at high rates of beneficial mutations, which generates strongly correlated clusters of fixed mutations nested in each other's background (the crossover between these regimes is further quantified below).

The Q344ter rod opsin mutation, along with two silent mutations which generated an AvrII restriction site designed for genotyping purposes, was introduced into an 11 kb BamHI-flanked genomic clone of the murine opsin gene [16].

These mutations found on APC are usually nonsense or frame shift mutations, which generate truncated forms of APC.

The RAM GFP constructs used throughout the present study have silent mutations which generate transcripts resistant to RAM siRNA.

This result would be in accordance with the work of Houle et al. [ 30], who suggested that parasite resistance is likely to be controlled by several loci and, therefore, may receive a strong mutation input, which generates genetic variation.