Sentence examples for mutation which does from inspiring English sources

Also, rs147564881 is a rare mutation which does not seem to be enriched within the Swedish CH patient group.

In these tests, the unc-13 mutation (which does not affect dauer formation) served to prevent the strain from avoiding the pathogen.

These date indicate that in the context of the Nef LL164/165AA mutation, which does not affect MHC-I down-regulation under native conditions [19], the fusion of the MHC-I CD to Nef generates a chimeric protein sequence that is recognized in T cells by the endosomal sorting machinery.

In fact, the formation of the common deletion is significantly reduced by this mutation, which does not affect the distribution of other mtDNA deletions in this haplogroup [ 44], suggesting that the reference sequence must be intact for the common deletion to occur.

Since the index report we have identified four unrelated patients of Somali ancestry with the same INSR mutation, which did not occur in any other patients with severe insulin resistance.

In accordance with a previous estimation [29], one third of the simulated variants are assumed to be synonymous mutations, which does not affect gene expression and are not included in our analysis.

This mode of evolution produces temporal clustering of fixations as a generic consequence of genetic linkage and high supply of beneficial mutations, which does not depend on details of the fitness landscape (Park and Krug 2007).

This may mean that the C-terminal region of type II NDs may be able to readily undergo mutations which does not affect the catalytic activity of the protein.

While poromas exhibited only few mutations, which did not involve TP53, the majority of porocarcinomas harboured UV-mediated mutations in TP53 with some of these cases showing considerable genetic heterogeneity that may be clinically exploitable.

Notably, disease-causing mutations identified in patients with mild phenotypes might be difficult to distinguish from benign mutations, which do not cause disease.

To better define the role of PTB in the FCV life cycle and to allow the generation of mutations which did not result in large scale disruption of the RNA secondary structure, we first determined the structure of the 5' end of the FCV genomic RNA using ribonuclease (RNase) digestion.