Sentence examples for mutation which has from inspiring English sources
Similarly, Hydroxyflutamide and other antagonists did not show any evidence of binding as an agonist in LNCaP cells harbouring the T877A mutation which has also been linked to paradoxical agonism53,54 (Supplementary Fig. S3b).
To investigate in Australian patients with glaucoma and normal controls the prevalence and associated phenotype of the WDR36 D658G mutation, which has previously been suggested to be a disease-causing mutation in pedigrees with primary open-angle glaucoma (POAG).
Biopsy is recommended for non-steatotic HCAs less than 5 cm to look for β-catenin mutation, which has a high risk of malignant transformation and needs resection.
The mutation, which has no obvious advantages, likely arose by chance in one individual and drifted to a high frequency in the Solomon Islands because the original population was small, says Jonathan Friedlaender, an anthropologist emeritus at Temple University in Philadelphia, Pennsylvania, who was not involved in the study.
By chance alone, it might be that they are both carrying a European mutation which has come together in their child".
In 663114, the dark waves of the tsunami are frightening and yet, when the cicada reemerges from the wreckage and radiation, it has undergone a severe mutation which has given it wings of rare beauty.
In addition, an amide-containing side chain (Asn193) and a loop in domain B (ΔIG mutation), which have been proven to be important for thermostability in corresponding position of other α-amylases, were also investigated.
In contrast, the S298E mutation, which had no effect on either cofactor-activated phosphorylation or affinity for chromatin, did not perturb the ability of Gro/TLE1 to inhibit neuronal differentiation (Fig. 7B E, cf. bars 2 and 8).
Sequencing showed the homozygous mutation, which had not been reported so far.
In this study, the definition of a genetic mutation is confined to the protein-truncating mutation and the missense mutation, which have a confirmed association to disease.
K71P mutation, which had a weaker effect on immunoblotting, also impaired the ability of RseP to cleave wild-type HA-MBP-YqfG during the 15 min chase period.
