Sentence examples for mutation we introduced from inspiring English sources

We tested whether the mutation we introduced (E457Q) would change hSGLT3 sugar K0.5s to render them similar to hSGLT1.

For the second mutation, we introduced a premature stop codon that truncated the BRCA1 protein by deleting the last 10 C-terminal amino acids.

To ask whether the presence of the serine at position 62 was responsible for the large impact of the T63S mutation, we introduced a S→T change at residue 62 to make a Kcv sequence, Kcv TT), that resembles the Kir2.1 filter sequence.

To test whether the R23E mutant effect could be neutralized by a second mutation, we introduced the inhibitory T49E mutation into the R23E variant.

Therefore, in order to confirm that the observed suppression by HU was specific to the erg26 -1 mutation, we introduced the erg26 -1 allele de novo into a WT strain of the W303 background.

To gain additional evidence that the L107C mutation we introduced into the NEMO1 120 and NEMO44 111 constructs does not compromise the protein's function, we introduced the L107C change into full-length NEMO and evaluated the activity of this construct in a range of cellular assays.

From this matrix, distance patterns are then extracted and summarized as a feature vector; To account for the atom changes induced by the mutation, we introduce a 'pharmacophore count' vector.

Moreover, it seems highly unlikely that the point mutations we introduced in the Syt1/7 chimera, or replacement of the linker region, might cause folding problems because all these mutated residues are surface exposed.

Therefore, the mutations we introduced into the Sosie C-terminus may have made this potential ER export signal inaccessible.

To genetically complement the insertion mutations, we introduced a genomic ARR22 DNA fragment into the arr22-2 and arr22-3 mutant lines.

To confirm the increase in antigen recognition capability by the amino acid mutations, we introduced the mutations observed in clone11 into the KM10 scFv gene.